Familial Mediterranean fever in Romania: a case report and literature review

Familial Mediterranean fever in Romania: a case report and literature review

Blog Article

Familial Mediterranean Fever (FMF) is a hereditary autoinflammatory disease characterized by recurrent fever and systemic inflammation, most prevalent in Eastern Mediterranean populations.Rare in regions like Romania, FMF presents diagnostic challenges and risks igora vibrance 4-99 severe complications if untreated.We report a 7-year-old Romanian girl, from a non-classical ethnic background, with recurrent febrile episodes and elevated inflammatory markers.Genetic testing confirmed a homozygous MEFV c.2082G>A (p.

Met694Ile) variant.Colchicine therapy reduced flare frequency and normalized inflammatory markers.FMF should be considered in atypical populations with color touch 7/97 recurrent inflammation.Genetic testing aids diagnosis in non-endemic regions, enabling early colchicine treatment to prevent complications.