SHORT LINEAR MOTIF ACQUISITION, EXON FORMATION AND ALTERNATIVE SPLICING DETERMINE A PATHWAY TO DIVERSITY FOR NCOR-FAMILY CO-REPRESSORS

Short linear motif acquisition, exon formation and alternative splicing determine a pathway to diversity for NCoR-family co-repressors

Vertebrate NCoR-family co-repressors play central roles in the timing of embryo and stem cell differentiation by repressing the activity of a range of transcription factors.They interact with nuclear receptors using short linear motifs (SLiMs) termed co-repressor for nuclear receptor (CoRNR) boxes.Here, we identify the pathway leading to increasing

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Nomilin and Its Analogues in Citrus Fruits: A Review of Its Health Promotion Effects and Potential Application in Medicine

Nomilin is one of the major limonoids, which are plant secondary metabolites also known as tetranortriterpenoids.Nomilin is found gassflaske mostly in common edible citrus fruits including lemons, limes, oranges, grapefruits, mandarins, along with traditional Chinese medicines derived from citrus fruits, such as tangerine seed, tangerine peel, fruc

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